From the construction of one-dimensional (1D) neutron scattering length density (SLD) profiles, we find that water penetrates into the hydrocarbon region up to and including the center of liquid-crystalline LPS bilayers. This result could have far-reaching implications as to how small molecules penetrate the outer membrane of Gram-negative bacteria.
Reference:
T. Abraham, S. Schooling, M.-P. Nieh, T.J. Beveridge and J. Katsaras.
Neutron Diffraction Study of Pseudomonas Aeruginosa Lipolysaccharide Bilayers
J. Phys. Chem. B 111, 2477 (2007)
learn more about Dr. Katsaras's projects